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KMID : 1189320160100030522
Asian Spine Journal
2016 Volume.10 No. 3 p.522 ~ p.527
Invasiveness Reduction of Recent Total En Bloc Spondylectomy: Assessment of the Learning Curve
Ishii Takayoshi

Murakami Hideki
Demura Satoru
Kato Satoshi
Yoshioka Katsuhito
Fujii Moriyuki
Igarashi Takashi
Tsuchiya Hiroyuki
Abstract
Study Design: Case-control study.

Purpose: To evaluate the surgical magnitude and learning curve of "second-generation" total en bloc spondylectomy (TES).

Overview of Literature: In June 2010, we developed second-generation TES combined with tumor-induced cryoimmunology, which does not require autograft harvesting.

Methods: TES was performed in 63 patients between June 2010 and September 2013. Three groups of patients were evaluated: 20 undergoing surgery in the first year of development of second-generation TES (group I), 20 in the second year (group II), and 23 in the third year (group III). Patient backgrounds showed no remarkable differences. Operating time, intraoperative blood loss, blood transfusion, and postoperative C-reactive protein and creatine phosphokinase were compared among the groups.

Results: Mean¡¾standard deviation operating time was 486¡¾130 minutes in group I, 441¡¾85 minutes in group II, and 396¡¾75 minutes in group III. The time was significantly shorter in group III than in group I (p<0.05). Intraoperative blood loss was 901¡¾646 mL in group I, 433¡¾177 mL in group II, and 411¡¾167 mL in group III. Blood loss was significantly lower in groups II and III than in group I (p<0.01). Transfusion was not required in 20 of 23 patients in group III, and mean C-reactive protein levels on postoperative day 3 were significantly lower in this group than in group I (6.12 mg/L vs. 10.07 mg/L; p<0.05). Postoperative creatine phosphokinase levels did not differ among the groups.

Conclusions: TES is associated with a significant learning curve. Thus, second-generation TES can no longer be considered highly invasive.
KEYWORD
Total en bloc spondylectomy, Learning curve
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